Article
Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast.
The Journal of cell biology - 1 Dec 1993
Tan P K, Davis N G, Sprague G F, Payne G S
Abstract excerpt
The role of clathrin in endocytosis of the yeast phermone receptors was examined using strains expressing a temperature-sensitive clathrin heavy chain. The yeast phermone receptors belong to the family of seven transmembrane segment, G-protein-coupled receptors. A rapid and reversible defect in u...
Topics
- Biological Transport
- Clathrin
- Endocytosis
- GTP-Binding Proteins
- Genes, Fungal
- Genotype
- Kinetics
- Mating Factor
- Peptides
- Pheromones
- Pronase
- Receptors, Mating Factor
- Receptors, Peptide
- Saccharomyces cerevisiae
- Temperature
- Transcription Factors
- Vacuoles