S. cerevisiae alpha pheromone receptors activate a novel signal transduction pathway for mating partner discrimination.

Abstract excerpt

Wild-type S. cerevisiae cells of both mating types prefer partners producing high levels of pheromone and mate very infrequently to cells producing no pheromone. However, some mutants that are supersensitive to pheromone lack this ability to discriminate. In this study, we provide evidence for a novel role of alpha pheromone receptors in mating partner discrimination that is independent of the known G...

Topics

• Actins
• Blotting, Northern
• Clathrin
• Genes, Fungal
• Microscopy, Fluorescence
• Morphogenesis
• Mutation
• Myosins
• Receptors, Cell Surface
• Receptors, Mating Factor
• Receptors, Peptide