Article
A role for clathrin in the sorting of vacuolar proteins in the Golgi complex of yeast.
The EMBO journal - 1 Aug 1992
Seeger M, Payne G S
Abstract excerpt
We have investigated the role of clathrin in vacuolar protein sorting using yeast strains harboring a temperature-sensitive allele of clathrin heavy chain (chc1-ts). After a 5 min incubation at the non-permissive temperature (37 degrees C), the chc1-ts strains displayed a severe defect in the sorting of lumenal vacuolar proteins. Sorting of a vacuolar membrane protein, alkaline phosphatase, and transport to the...
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