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Article

Dextromethorphan O-demethylation polymorphism in Jordanians.

European journal of clinical pharmacology - 1 Jan 1993

Irshaid Y M, al-Hadidi H F, Rawashdeh N M

Abstract excerpt

The O-demethylation of dextromethorphan (DMT) to dextrorphan (DRP) was studied in 241 unrelated, healthy Jordanian volunteers (171 males, 70 females). Urine was collected for 8 h following a single oral dose of DMT bromhydrate 30 mg. A thin-layer chromatographic (TLC) technique was used to identify the metaboliser phenotype. The frequency of the poor metaboliser phenotype was found to be 2.9% (approximate 95%...

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Source

Identifiers

PMID: 8276053
DOI: 10.1007/BF00315395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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