Article
Induction of immature thymocyte proliferation after castration of normal male mice.
Endocrinology - 1 Jan 1994
Olsen N J, Viselli S M, Shults K, Stelzer G, Kovacs W J
Abstract excerpt
The physiological basis and immunological significance of thymic enlargement in castrate male animals is not known. We used normal male C57 Bl/6 mice to examine the contribution of in situ thymocyte proliferation to castration-induced enlargement of the thymus. Animals castrated at 8-10 weeks of age were compared to normal intact males. Thymocytes were examined 4-120 days after castration using flow cytometry to...
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