Article
Induction of immature thymocyte proliferation after castration of normal male mice.
Endocrinology - 1 Jan 1994
Olsen N J, Viselli S M, Shults K, Stelzer G, Kovacs W J
Abstract excerpt
The physiological basis and immunological significance of thymic enlargement in castrate male animals is not known. We used normal male C57 Bl/6 mice to examine the contribution of in situ thymocyte proliferation to castration-induced enlargement of the thymus. Animals castrated at 8-10 weeks of...
Topics
- Animals
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Cell Division
- Cellular Senescence
- Male
- Mice
- Mice, Inbred C57BL
- Orchiectomy
- Phenotype
- Thymus Gland