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Article

Thymotrophic effect of ether lipid 1-O-octadecyl-2-O-methoxy-rac-glicero-3-phosphocholine in the mouse.

Immunopharmacology - 1 Oct 1997

Cardile V, Mudò G, Jiang X, Casella F, Bindoni M, Belluardo N

Abstract excerpt

1-O-octadecyl-2-O-methoxy-rac-glicero-3-phosphocholine (ET-18-OCH3) is a synthetic derivate of 2-lysophosphatidyl-choline, endowed with some immunomodulatory and anticancer effects. In the present work we report that a chronic (1 microgram/g b.w. for 2 weeks) or acute single dose injection of ET-18-OCH3 produced a recovery of thymus weight and thymocytes cellularity in two different strains of mice, C57BL6 and...

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Identifiers

PMID: 9403339
DOI: 10.1016/s0162-3109(97)00049-0

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