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Article

Androgen deprivation induces phenotypic and functional changes in the thymus of adult male mice.

Endocrinology - 1 Nov 1991

Olsen N J, Watson M B, Henderson G S, Kovacs W J

Abstract excerpt

The functional immunological consequences of thymic regeneration after castration were studied in adult male C57Bl/6 mice. Phenotypic profiles of thymocytes present in the enlarged thymuses of castrate animals demonstrated a significant decrease in the proportion of thymocytes positive for the suppressor/cytotoxic phenotype (CD4-CD8+; P = 0.005). Thymic enlargement in castrate animals was accompanied by increased...

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Identifiers

PMID: 1834454
DOI: 10.1210/endo-129-5-2471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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