Androgen deprivation induces phenotypic and functional changes in the thymus of adult male mice.

doi:10.1210/endo-129-5-2471

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Article

Androgen deprivation induces phenotypic and functional changes in the thymus of adult male mice.

Endocrinology - 1 Nov 1991

Olsen N J, Watson M B, Henderson G S, Kovacs W J

Abstract excerpt

The functional immunological consequences of thymic regeneration after castration were studied in adult male C57Bl/6 mice. Phenotypic profiles of thymocytes present in the enlarged thymuses of castrate animals demonstrated a significant decrease in the proportion of thymocytes positive for the su...

Topics

Androgens
Animals
CD4-CD8 Ratio
Castration
Flow Cytometry
Male
Mice
Organ Size
Phenotype
Spleen
T-Lymphocytes, Regulatory
Testosterone
Thymidine
Thymus Gland

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