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Article

Androgen receptor gene mutations in hormone-refractory prostate cancer.

The Journal of pathology - 1 Dec 1999

Wallén M J, Linja M, Kaartinen K, Schleutker J, Visakorpi T

Abstract excerpt

Prostate cancer is considered to be one of the most hormone-dependent human malignancies. As a key mediator of hormonal response, the androgen receptor (AR) is believed to have an important role in the progression of prostate cancer. Mutations in the coding region of the AR gene have been found in both untreated and hormone-refractory prostate cancer, but the frequency of such mutations at different stages of the...

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Source

Identifiers

PMID: 10629558
DOI: 10.1002/(SICI)1096-9896(199912)189:4<559::AID-PATH471>3.0.CO;2-Y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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