Androgen receptor gene mutations in prostate cancer. Implications for disease progression and therapy.

Abstract excerpt

Recent studies indicate that androgen receptors are present in all histological types of prostatic tumours, in relapsed prostatic carcinomas and in tumour metastases, even those obtained from patients in whom endocrine therapy was unsuccessful. Several research groups have asked whether structura...

Topics

• Humans
• Male
• Mutation
• Prostatic Neoplasms
• Receptors, Androgen
• Structure-Activity Relationship
• Tumor Cells, Cultured