Article
A genetic sequence change in the 3'-noncoding region of the androgen receptor gene in prostate carcinoma.
European urology - 1 Jan 1997
Paz A, Lindner A, Zisman A, Siegel Y
Abstract excerpt
OBJECTIVE: We intended to identify structural changes in the hormone-binding domain and C-terminal region of the androgen receptor (AR) gene in carcinoma of prostate specimens. METHODS: Twelve prostate cancer specimens from prostate resections were analyzed for the presence of mutations in the E-H exons and part of the 3'-untranslated region of the AR cDNA, using RT-PCR and direct sequencing. RESULTS: A...
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