A genetic sequence change in the 3'-noncoding region of the androgen receptor gene in prostate carcinoma.

doi:10.1159/000474452

Back to search

Article

A genetic sequence change in the 3'-noncoding region of the androgen receptor gene in prostate carcinoma.

European urology - 1 Jan 1997

Paz A, Lindner A, Zisman A, Siegel Y

Abstract excerpt

OBJECTIVE: We intended to identify structural changes in the hormone-binding domain and C-terminal region of the androgen receptor (AR) gene in carcinoma of prostate specimens. METHODS: Twelve prostate cancer specimens from prostate resections were analyzed for the presence of mutations in the E-...

Topics

Adenocarcinoma
Aged
Alleles
DNA Mutational Analysis
DNA Primers
DNA, Complementary
DNA, Neoplasm
Electrophoresis, Agar Gel
Exons
Humans
Male
Middle Aged
Mutation
Neoplasm Staging
Polymerase Chain Reaction
Prostatectomy
Prostatic Neoplasms
RNA, Messenger

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.