Article
Mutations in the Drosophila melanogaster gene three rows permit aspects of mitosis to continue in the absence of chromatid segregation.
Journal of cell science - 1 Sept 1993
Philp A V, Axton J M, Saunders R D, Glover D M
Abstract excerpt
We have cloned the three rows (thr) gene, by a combination of chromosome microdissection and P element tagging. We describe phenotypes of embryos homozygous for mutations at the thr locus. Maternal mRNA and protein appear to be sufficient to allow 14 rounds of mitosis in embryos homozygous for th...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Division
- Chromatids
- Cloning, Molecular
- Cyclins
- Drosophila Proteins
- Drosophila melanogaster
- Genes, Insect
- Genes, Lethal
- Insect Hormones
- Metaphase
- Mitosis
- Molecular Sequence Data
- Phenotype