Article
The Drosophila maternal-effect mutation grapes causes a metaphase arrest at nuclear cycle 13.
Development (Cambridge, England) - 1 Aug 1994
Fogarty P, Kalpin R F, Sullivan W
Abstract excerpt
grapes (grp) is a second chromosome (36A-B) maternal-effect lethal mutation in Drosophila melanogaster. We demonstrate that the syncytial nuclear divisions of grp-derived embryos are normal through metaphase of nuclear cycle 12. However, as the embryos progress into telophase of cycle 12, the mic...
Topics
- Animals
- Cell Nucleus
- Checkpoint Kinase 1
- Drosophila Proteins
- Drosophila melanogaster
- Embryo, Nonmammalian
- Female
- Fluorescent Antibody Technique
- Genes, Insect
- Metaphase
- Microtubules
- Morphogenesis
- Mutation
- X-Rays