Article
Control of mitotic entry after DNA damage in Drosophila.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004
Jaklevic Burnley, Purdy Amanda, Su Tin Tin
Abstract excerpt
In the presence of DNA damage, cells delay the entry into mitosis, presumably to allow time for repair. Methods to detect the delay of mitosis in a multicellular model organism, Drosophila melanogaster, are described here. These include the collection of embryos and larvae, irradiation with x-rays to damage DNA, and fixing and staining of tissues with an antibody to phosphorylated histone H3 to measure the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
