Article
Zebrafish maternal-effect mutations causing cytokinesis defect without affecting mitosis or equatorial vasa deposition.
Mechanisms of development - 1 Jan 2004
Kishimoto Yasuyuki, Koshida Sumito, Furutani-Seiki Makoto, Kondoh Hisato
Abstract excerpt
Maternal-effect genes play essential roles in early embryogenesis particularly before activation of the zygotic genes. A genetic screen for mutations affecting such maternal-effect genes was carried out employing an F3 screen strategy, identifying six recessive mutations out of 60 mutagenized genomes. Three of the mutations (acytokinesis mutations: ackkt5, ackkt62 and ackkt119) caused absence of cell cleavage in...
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