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Article

The three rows gene of Drosophila melanogaster encodes a novel protein that is required for chromosome disjunction during mitosis.

Molecular biology of the cell - 1 Nov 1993

D'Andrea R J, Stratmann R, Lehner C F, John U P, Saint R

Abstract excerpt

Zygotic expression of the three rows (thr) gene of Drosophila melanogaster is required for normal cell proliferation during embryogenesis. Mitotic defects in thr mutant embryos begin during mitosis 15, and all subsequent divisions are disrupted. Chromosome disjunction and consequently cytokinesis fail during these defective mitoses, although the initial mitotic processes (chromosome condensation, spindle...

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Identifiers

PMID: 8305737
DOI: 10.1091/mbc.4.11.1161
PMCID: PMC275751

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