Article
Tracking H-2 alleles in transgenic mice by RFLP and heteroduplex analysis.
Transgenic research - 1 May 1996
Shanmugam V, Haines D, Lake J P, Saha B K
Abstract excerpt
Transgenic mice provide valuable tools for biological research including many areas of immunology. In studies involving the major histocompatibility complex (MHC), it is often necessary to place the desired transgene in a specific H-2 (the murine MHC) environment. In this regard, the strains comm...
Topics
- Alleles
- Animals
- Base Sequence
- Genetic Markers
- H-2 Antigens
- Mice
- Mice, Transgenic
- Microsatellite Repeats
- Molecular Sequence Data
- Nucleic Acid Heteroduplexes
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Sequence Alignment
- Sequence Homology, Nucleic Acid
