Article
Molecular mapping of murine I region recombinants. III. Crossing over at two discrete sites within the beta 1-beta 2 intron of the E beta gene.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1991
Padgett K A, Shreffler D C, Saha B K
Abstract excerpt
The murine MHC provides a unique genetic system for studying meiotic recombination. A large number of murine H-2 recombinants cross over within a stretch of the E beta gene referred to as the E beta hot spot. The crossing over of eight such recombinants, derived from the s and k haplotypes, was studied at the nucleotide level. A 3-kb stretch of DNA, 3' to the beta 1 exon of the E beta gene, was sequenced after...
Topics
- Alleles
- Animals
- Base Sequence
- Crossing Over, Genetic
- H-2 Antigens
- Introns
- Mice
- Molecular Sequence Data
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
