Article
The complete nucleotide sequence of two cold-adapted, temperature-sensitive attenuated mutant vaccine viruses (cp12 and cp45) derived from the JS strain of human parainfluenza virus type 3 (PIV3).
Virus research - 1 Oct 1993
Stokes A, Tierney E L, Sarris C M, Murphy B R, Hall S L
Abstract excerpt
Two cold-passaged mutant vaccine viruses (cp12 and cp45) derived from the JS wild-type (wt) strain of human parainfluenza virus type 3 (PIV3) have been sequenced. These mutant viruses display the cold-adapted (ca), temperature-sensitive (ts), and attenuation (att) phenotypes. Sequence data indica...
Topics
- Adaptation, Physiological
- Amino Acid Sequence
- Base Sequence
- Cold Temperature
- Molecular Sequence Data
- Mutation
- Parainfluenza Virus 3, Human
- Vaccines, Attenuated
- Viral Vaccines