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Article

BRO1, a novel gene that interacts with components of the Pkc1p-mitogen-activated protein kinase pathway in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jun 1996

Nickas M E, Yaffe M P

Abstract excerpt

Yeast cells with mutations in BRO1 display phenotypes similar to those caused by deletion of BCK1, a gene encoding a MEK kinase that functions in a mitogen-activated protein kinase pathway mediating maintenance of cell integrity. bro1 cells exhibit a temperature-sensitive growth defect that is suppressed by the addition of osmotic stabilizers or Ca2+ to the growth medium or by additional copies of the BCK1 gene....

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Identifiers

PMID: 8649366
DOI: 10.1128/MCB.16.6.2585
PMCID: PMC231249

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