Article
BRO1, a novel gene that interacts with components of the Pkc1p-mitogen-activated protein kinase pathway in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jun 1996
Nickas M E, Yaffe M P
Abstract excerpt
Yeast cells with mutations in BRO1 display phenotypes similar to those caused by deletion of BCK1, a gene encoding a MEK kinase that functions in a mitogen-activated protein kinase pathway mediating maintenance of cell integrity. bro1 cells exhibit a temperature-sensitive growth defect that is su...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Calcium
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Division
- Cloning, Molecular
- DNA, Fungal
- Genes, Fungal
- Helminth Proteins
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Kinase C
- Restriction Mapping
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid