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Article

The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast.

DNA repair - 10 Nov 2011

George Carolyn M, Lyndaker Amy M, Alani Eric

Abstract excerpt

In the early steps of homologous recombination, single-stranded DNA (ssDNA) from a broken chromosome invades homologous sequence located in a sister or homolog donor. In genomes that contain numerous repetitive DNA elements or gene paralogs, recombination can potentially occur between non-allelic/divergent (homeologous) sequences that share sequence identity. Such recombination events can lead to lethal...

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Identifiers

PMID: 21978436
DOI: 10.1016/j.dnarep.2011.07.007
PMCID: PMC3201711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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