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Article

Analysis of DNA double-strand break repair pathways in mice.

Mutation research - 3 Jan 2007

Brugmans Linda, Kanaar Roland, Essers Jeroen

Abstract excerpt

During the last years significant new insights have been gained into the mechanism and biological relevance of DNA double-strand break (DSB) repair in relation to genome stability. DSBs are a highly toxic DNA lesion, because they can lead to chromosome fragmentation, loss and translocations, eventually resulting in cancer. DSBs can be induced by cellular processes such as V(D)J recombination or DNA replication....

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PMID: 16797606
DOI: 10.1016/j.mrfmmm.2006.01.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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