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Article

Association of HLA-DQB1*0201 with stiff-man syndrome.

The Journal of clinical endocrinology and metabolism - 1 Dec 1993

Pugliese A, Solimena M, Awdeh Z L, Alper C A, Bugawan T, Erlich H A, De Camilli P, Eisenbarth G S

Abstract excerpt

Stiff-man syndrome (SMS) is a rare disorder of the central nervous system of probable autoimmune origin. Patients with SMS often have other autoimmune diseases, in particular type I (insulin-dependent) diabetes mellitus (IDDM). Approximately 60% of patients with SMS have high titers of autoantibodies against the enzyme glutamic acid decarboxylase. Similar to SMS, the majority of patients with IDDM have...

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Source

Identifiers

PMID: 8263140
DOI: 10.1210/jcem.77.6.8263140

Genes

SMS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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