Article
Association of HLA-DR and -DQ alleles with idiopathic achalasia.
Gastroenterology - 1 Jul 1999
Verne G N, Hahn A B, Pineau B C, Hoffman B J, Wojciechowski B W, Wu W C
Abstract excerpt
BACKGROUND & AIMS: Idiopathic achalasia is a motility disorder of the esophagus characterized by incomplete relaxation of the lower esophageal sphincter and a loss of normal peristaltic activity in the body of the esophagus. The loss of inhibitory neurons in the distal esophagus, as well as abnormalities in the vagus nerve, dorsal motor nucleus of the vagus nerve, and autonomic nervous system, have been described...
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