Association of X-linked adrenoleukodystrophy with HLA DRB1 alleles.

doi:10.1006/bbrc.1995.2643

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Article

Association of X-linked adrenoleukodystrophy with HLA DRB1 alleles.

Biochemical and biophysical research communications - 13 Nov 1995

Berger J, Bernheimer H, Faé I, Braun A, Roscher A, Molzer B, Fischer G

Abstract excerpt

Inflammatory demyelination in the central nervous system in the childhood cerebral phenotype of X-linked adrenoleukodystrophy (X-ALD) bears resemblance to that of multiple sclerosis. With a view to an association of HLA class II genes, specifically HLA-DRB1 subtype DRB1*15 to multiple sclerosis w...

Topics

Adrenoleukodystrophy
Alleles
Brain
Cells, Cultured
Child
DNA
Fibroblasts
Genes, MHC Class II
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Leukocytes
Multiple Sclerosis
Phenotype
X Chromosome

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