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Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy Is Associated with HLA‐A 3303 and HLA‐DPB1 0501

24 Feb 2024

Abstract excerpt

We determined the genetic association between specific human leucocyte antigen (HLA) loci and autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy. Our results showed that autoimmune GFAP astrocytopathy was associated with HLA‐A*3303 (odds ratio [OR] = 2.02, 95% confidence interval [CI] = 1.32–3.06, p = 0.00072, p adj. = 0.046) and HLA‐DBP1*0501 (OR = 0.51, 95% CI = 0.36–0.71, p = 0.000048, p adj. =...

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PMID: 38400794
DOI: 10.1002/ana.26899

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