Liquid hybridization analysis of TSH receptor mRNA in normal and abnormal human thyroid tissues.

doi:10.1089/thy.1993.3.219

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Article

Liquid hybridization analysis of TSH receptor mRNA in normal and abnormal human thyroid tissues.

Thyroid : official journal of the American Thyroid Association - 1 Jan 1993

Tomer Y, Graves P N, Jin A, Schwartz A E, Friedman E W, Davies T F

Abstract excerpt

Radiolabeled human TSH receptor (hTSHR) cRNA probes encoding nucleotides 37-2298 and 37-209, with unlabeled sense RNA control segments, were used in a liquid hybridization assay and found to be highly specific and sensitive enabling detection of 0.5 fmol of hTSHR mRNA. Using normal human thyroid monolayer cell cultures we calculated that the average number of TSHR mRNA transcripts was 95 +/- 5 per cell under in...

Topics

Adenoma
Adult
Aged
Carcinoma, Papillary
Female
Fetus
Gestational Age
Goiter
Graves Disease
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nucleic Acid Hybridization

RNA Probes

RNA, Messenger

Receptors, Thyrotropin

Reference Values

Source

Open in PubMed

Identifiers

PMID: 8257862
DOI: 10.1089/thy.1993.3.219

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8257862-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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