Article
Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues.
The Journal of clinical endocrinology and metabolism - 1 Nov 1994
Paschke R, Metcalfe A, Alcalde L, Vassart G, Weetman A, Ludgate M
Abstract excerpt
The TSH receptor (TSHR) has been proposed as an antigenic link between the thyroid and the orbit; TSHR transcripts have been demonstrated by other groups, one in orbital tissue and the other in orbital and dermal fibroblasts. In a previous study we were unable to demonstrate transcripts for the c...
Topics
- Actins
- Base Sequence
- Blotting, Southern
- Cell Line
- Cyclic AMP
- DNA
- DNA, Complementary
- Eye
- Fibroblasts
- Gene Amplification
- Genetic Variation
- Glycosaminoglycans
- Humans
- Molecular Sequence Data
- Muscles
- Polymerase Chain Reaction
- RNA, Messenger
- Receptors, Thyrotropin