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Article

Identification of a minor Tg mRNA transcript in RNA from normal and goitrous thyroids.

Molecular and cellular endocrinology - 1 Mar 1992

Targovnik H M, Cochaux P, Corach D, Vassart G

Abstract excerpt

Polymerase chain reaction (PCR) amplification of nt 4502 to nt 5184 of the thyroglobulin (Tg) mRNA from several patients, with or without elevated serum thyrotropin (TSH), showed a predominant fragment of the expected size (683 bp) and a minor fragment of 512 bp. The sequence of this minor fragment revealed that 171 bp were missing between position 4567 and 4737. It is highly probable that the deleted sequence...

Topics

Amino Acid Sequence
Base Sequence
Goiter
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
RNA Splicing
RNA, Messenger
Thyroglobulin
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1639210
DOI: 10.1016/0303-7207(92)90087-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1639210-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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