Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human leucocyte antigen DNA typing in Singaporean Chinese patients with Graves' disease.

Annals of the Academy of Medicine, Singapore - 1 Jul 1993

Chan S H, Lin Y N, Wee G B, Ren E C, Lui K F, Cheah J S

Abstract excerpt

Human Leucocyte Antigen (HLA) A, B, C, DR, DQ and DP locus alleles in 35 Chinese patients with Graves' disease and 80 controls were typed for using serological and DNA polymerase chain reaction/sequence specific oligonucleotide (PCR/SSO) methods. B46 was found to be strongly associated with male patients (p = 0.0002; RR = 8.2, 95% confidence interval 2.1-32.2). In HLA class 1 alleles, besides B46, the frequencies...

Topics

Adult
Alleles
China
Cross-Cultural Comparison
DNA
Gene Frequency
Graves Disease
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Risk Factors

Singapore

Source

Identifiers

PMID: 8257062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8257062-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human leucocyte antigen DNA typing in Singaporean Chinese patients with Graves' disease.PMID 8257062Read ↗

The HLA-DQ associations with Graves' disease in Chinese children.Semantic proximity Read ↗

The association of HLA -A, -B, and -DRB1 genotypes with Graves' disease in Taiwanese people.Semantic proximity Read ↗

The HLA-B*4601-DRB1*0901 haplotype is positively correlated with juvenile ocular myasthenia gravis in a southern Chinese Han population.Semantic proximity Read ↗

Association between HLA-B*46 allele and Graves disease in Asian populations: a meta-analysis.Semantic proximity Read ↗

HLA class II alleles in Japanese patients with Graves' disease: weak associations of HLA-DR and -DQ.Semantic proximity Read ↗

The association between HLA class II haplotype with Graves' disease in Thai population.Semantic proximity Read ↗

Identification of HLA-DRB1 alleles associated with Graves' disease in Koreans by sequence-based typing.Semantic proximity Read ↗

The human leukocyte antigen HLA DRB3*020/DQA1*0501 haplotype is associated with Graves' disease in African Americans.Semantic proximity Read ↗

HLA-DRB3 gene alleles in Caucasian patients with Graves' disease.Semantic proximity Read ↗

Association of HLA-DQA1*0501 with Graves' disease in English Caucasian men and women.Semantic proximity Read ↗

[Correlation study between Chinese myasthenia gravis patients from Guangdong province and the polymorphism of HLA immunogene].Semantic proximity Read ↗

Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.