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Article

The human leukocyte antigen HLA DRB3020/DQA10501 haplotype is associated with Graves' disease in African Americans.

The Journal of clinical endocrinology and metabolism - 1 Apr 2000

Chen Q Y, Nadell D, Zhang X Y, Kukreja A, Huang Y J, Wise J, Svec F, Richards R, Friday K E, Vargas A, Gomez R, Chalew S, Lan M S, Tomer Y, Maclaren N K

Abstract excerpt

Information on genetic susceptibility to Graves' disease in African Americans is limited. We studied DRB1, DQB1, DRB3 subtypes, DQA1*0501, DQA1*0201, and CTLA-4 polymorphisms in 49 African American patients with adult onset Graves' disease and 47 racially-matched controls using PCR-based sequence-specific priming methods. There were no significant differences in DRB1 or DQB1 allelic frequencies or CTLA-4...

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Identifiers

PMID: 10770195
DOI: 10.1210/jcem.85.4.6523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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