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Article

Persistence of four related human immunodeficiency virus subtypes during the course of zidovudine therapy: relationship between virion RNA and proviral DNA.

Journal of virology - 1 Jan 1994

Zhang Y M, Dawson S C, Landsman D, Lane H C, Salzman N P

Abstract excerpt

Human immunodeficiency virus (HIV) virion RNA and proviral DNA sequences have been examined over a 1-year period in an HIV-seropositive patient, commencing with the start of zidovudine treatment. By characterizing the variable V3 and V4 env domains, four related but structurally discrete genotypes could be identified prior to the start of therapy and during the subsequent 60-week period of therapy. Each of the...

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Identifiers

PMID: 8254752
DOI: 10.1128/JVI.68.1.425-432.1994
PMCID: PMC236302

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