Article
Discontinuous sequence change of human immunodeficiency virus (HIV) type 1 env sequences in plasma viral and lymphocyte-associated proviral populations in vivo: implications for models of HIV pathogenesis.
Journal of virology - 1 Nov 1991
Simmonds P, Zhang L Q, McOmish F, Balfe P, Ludlam C A, Brown A J
Abstract excerpt
Sequence change in different hypervariable regions of the external membrane glycoprotein (gp120) of human immunodeficiency virus type 1 (HIV-1) was studied. Viral RNA associated with cell-free virus particles circulating in plasma and proviral DNA present in HIV-infected peripheral blood mononucl...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Base Sequence
- Biological Evolution
- Genes, env
- Genetic Variation
- HIV Envelope Protein gp120
- HIV-1
- Hemophilia A
- Humans
- Lymphocytes
- Molecular Sequence Data
- Oligodeoxyribonucleotides