Article
HIV-1 proviral genotypes from the peripheral blood mononuclear cells of an infected patient are differentially represented in expressed sequences.
Journal of acquired immune deficiency syndromes - 1 Oct 1993
Michael N L, Chang G, Ehrenberg P K, Vahey M T, Redfield R R
Abstract excerpt
The RNA genome of the human immunodeficiency virus type 1 (HIV-1) is established as proviral DNA in infected cells. Only some of these cells may actively produce the array of viral RNAs that support progeny virion production. In vivo expression of a subset of proviral genotypes could influence the experimental characterization of the viral quasispecies. We have explored the relationship between DNA and cDNA...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Consensus Sequence
- DNA, Viral
- Gene Expression Regulation, Viral
- Genetic Variation
- Genotype
- HIV Envelope Protein gp120
- HIV Infections