Article
Papillomavirus-associated squamous skin cancers following transplant immunosuppression: one Notch closer to control.
Cancer treatment reviews - 1 Mar 2014
Connolly Kate, Manders Pete, Earls Peter, Epstein Richard J
Abstract excerpt
The frequent occurrence of cutaneous squamous cell carcinomas (SCCs) containing weakly tumorigenic human papillomaviruses (HPVs) following iatrogenic immunosuppression for organ transplantation remains incompletely understood. Here we address this problem in the light of recent insights into (1) the association of low-risk β-HPVs with skin SCCs in the rare genetic syndromes of epidermodysplasia verruciformis and...
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