Article
Segregation analyses of 1,476 population-based Australian families affected by prostate cancer.
American journal of human genetics - 1 May 2001
Cui J, Staples M P, Hopper J L, English D R, McCredie M R, Giles G G
Abstract excerpt
Segregation analyses aim to detect genetic factors that have a major effect on an individual's risk of disease and to describe them in terms of mode of inheritance, age-specific cumulative risk (penetrance), and allele frequency. We conducted single- and two-locus segregation analyses of data from 1,476 men with prostate cancer diagnosed at age <70 years and ascertained through population registries in Melbourne,...
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