Article
The c-fos gene and early-onset familial Alzheimer's disease.
Neuroscience letters - 17 Sept 1993
Bonnycastle L L, Yu C E, Wijsman E M, Orr H T, Patterson D, Clancy K P, Goddard K A, Alonso M E, Nemens E, White J A
Abstract excerpt
A gene for early-onset familial Alzheimer's disease (FAD) is located on chromosome 14q24.3. The c-fos gene (FOS) is also located in the same band of this chromosome and is thus a candidate for the FAD locus. A yeast artificial chromosome (YAC) clone was identified which contains FOS. This YAC als...
Topics
- Alleles
- Alzheimer Disease
- Base Sequence
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 14
- DNA
- Exons
- Genes, fos
- Genetic Linkage
- Humans
- Molecular Sequence Data
- Pedigree
- Polymerase Chain Reaction