Article
No association between c-fos gene polymorphisms and sporadic Alzheimer's disease.
Psychiatry and clinical neurosciences - 1 Dec 1996
Dai X Y, Hattori M, Yoshizawa J, Matsuda H, Arai H, Akizuki S, Nanko S
Abstract excerpt
Although ApoE epsilon 4 is a major risk factor for sporadic Alzheimer's disease (AD), 20-30% of sporadic AD patients do not have this allele. This indicates that other risk factors are involved in the pathogenesis of sporadic AD. Studies of the genetic association between AD and polymorphisms in the c-fos gene, a candidate gene for AD, were conducted. The polymorphisms of DsaI in exon 2 and Sau3 AI in intron 2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.