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Article

Genetic suppression of defective profilin by attenuated Myosin II reveals a potential role for Myosin II in actin dynamics in vivo in fission yeast.

Molecular biology of the cell - 1 Sept 2020

Zambon Paola, Palani Saravanan, Jadhav Shekhar Sanjay, Gayathri Pananghat, Balasubramanian Mohan K

Abstract excerpt

The actin cytoskeleton plays a variety of roles in eukaryotic cell physiology, ranging from cell polarity and migration to cytokinesis. Key to the function of the actin cytoskeleton is the mechanisms that control its assembly, stability, and turnover. Through genetic analyses in Schizosaccharomyces pombe, we found that myo2-S1 (myo2-G515D), a Myosin II mutant allele, was capable of rescuing lethality caused by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32614646
DOI: 10.1091/mbc.E20-04-0224
PMCID: PMC7530902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic suppression of defective profilin by attenuated Myosin II reveals a potential role for Myosin II in actin dynamics in vivo in fission yeast.PMID 32614646Read ↗

Type II myosin heavy chain encoded by the myo2 gene composes the contractile ring during cytokinesis in Schizosaccharomyces pombe.Semantic proximity Read ↗

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Type II myosin involved in cytokinesis in the fission yeast,Schizosaccharomyces pombeSemantic proximity Read ↗

Insight into actin organization and function in cytokinesis from analysis of fission yeast mutants.Semantic proximity Read ↗

Identification of a second myosin-II in Schizosaccharomyces pombe: Myp2p is conditionally required for cytokinesis.Semantic proximity Read ↗

Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.Semantic proximity Read ↗

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Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis.Semantic proximity Read ↗

Evidence for F-actin-dependent and -independent mechanisms involved in assembly and stability of the medial actomyosin ring in fission yeast.Semantic proximity Read ↗

Myosin-II reorganization during mitosis is controlled temporally by its dephosphorylation and spatially by Mid1 in fission yeast.Semantic proximity Read ↗

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