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Article

Novel variant isoform of G-CSF receptor involved in induction of proliferation of FDCP-2 cells: relevance to the pathogenesis of myelodysplastic syndrome.

Journal of cellular physiology - 1 Jun 2002

Awaya Norihiro, Uchida Hideo, Miyakawa Yoshitaka, Kinjo Kentaro, Matsushita Hiromichi, Nakajima Hideaki, Ikeda Yasuo, Kizaki Masahiro

Abstract excerpt

Recent studies have shown that point mutations in granulocyte colony-stimulating factor receptor (G-CSFR) are involved in the pathogenesis of severe congenital neutropenia (SCN) and in the transformation of SCN to acute myelogenous leukemia (AML). It is reasonably speculated that the abnormalities in the signal transduction pathways for G-CSF could be partly responsible for the pathogenesis and the development to...

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PMID: 12012328
DOI: 10.1002/jcp.10102

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STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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