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Article

The role of the granulocyte colony-stimulating factor receptor (G-CSF-R) in disease.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2007

Ward Alister C

Abstract excerpt

Granulocyte colony-stimulating factor (G-CSF) is a key regulator of granulopoiesis via stimulation of a specific cell-surface receptor, the G-CSF-R, found on hematopoietic progenitor cells as well as neutrophilic granulocytes. It is perhaps not surprising, therefore, that mutations of the G-CSF-R has been implicated in several clinical settings that affect granulocytic differentiation, particularly severe...

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Identifiers

PMID: 17127322
DOI: 10.2741/2086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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