Article
Positive feedback in the activation of G1 cyclins in yeast.
Nature - 27 Jun 1991
Dirick L, Nasmyth K
Abstract excerpt
Yeast cells become committed to the mitotic cell cycle at a stage during G1 called Start. To enter Start, cells must grow to a critical size. They also require the CDC28 protein kinase and at least one of three G1-specific cyclins encoded by CLN1, 2, and 3. It is thought that Start is triggered b...
Topics
- Cyclins
- Enzyme Activation
- Feedback
- G1 Phase
- Genes, Fungal
- Mutation
- Protein Kinases
- Saccharomyces cerevisiae
- Temperature
- Transcription, Genetic