Article
The transactivation potential of variant hepatocyte nuclear factor 1 is modified by alternative splicing.
The Journal of biological chemistry - 5 Dec 1993
Ringeisen F, Rey-Campos J, Yaniv M
Abstract excerpt
Two forms of the transcription factor vHNF1 (HNF1 beta or LFB3) have been previously described, derived by alternative splicing from a common premessenger RNA, and have been called vHNF1-A and vHNF1-B. vHNF1 proteins share a homologous homeo-related DNA-binding domain with the HNF1 protein, initially characterized as a liver-restricted transcription factor, and bind to a similar sequence motif. Here we...
Topics
- Animals
- Base Sequence
- Binding, Competitive
- Cell Line
- DNA Primers
- DNA-Binding Proteins
- Female
- Genetic Variation
- Hepatocyte Nuclear Factor 1
- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1-beta