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Article

The influence of HLA-DR and -DQ alleles on progression to multiple sclerosis following a clinically isolated syndrome.

Human immunology - 1 Jul 1993

Kelly M A, Cavan D A, Penny M A, Mijovic C H, Jenkins D, Morrissey S, Miller D H, Barnett A H, Francis D A

Abstract excerpt

A 5-year follow-up study was performed on 70 Caucasian patients presenting with isolated neurological syndromes of the optic nerve, brain stem, or spinal cord to assess the risk of progression to MS. The influence on patient prognosis of HLA-DR and -DQ alleles and presentation with disseminated brain lesions, demonstrated by MRI scanning, was determined. Clinical progression to MS was observed in 61% of optic...

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Identifiers

PMID: 8244781
DOI: 10.1016/0198-8859(93)90184-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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