Article
The influence of HLA-DR and -DQ alleles on progression to multiple sclerosis following a clinically isolated syndrome.
Human immunology - 1 Jul 1993
Kelly M A, Cavan D A, Penny M A, Mijovic C H, Jenkins D, Morrissey S, Miller D H, Barnett A H, Francis D A
Abstract excerpt
A 5-year follow-up study was performed on 70 Caucasian patients presenting with isolated neurological syndromes of the optic nerve, brain stem, or spinal cord to assess the risk of progression to MS. The influence on patient prognosis of HLA-DR and -DQ alleles and presentation with disseminated b...
Topics
- Adult
- Alleles
- Base Sequence
- Demyelinating Diseases
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Magnetic Resonance Imaging
- Middle Aged
- Molecular Sequence Data
- Multiple Sclerosis
- Optic Neuritis