Article
HLA-DRB1*1501 tagging rs3135388 polymorphism is not associated with neuromyelitis optica.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2010
Matiello Marcelo, Schaefer-Klein Janet, Brum Doralina G, Atkinson Elizabeth J, Kantarci Orhun H, Weinshenker Brian G
Abstract excerpt
BACKGROUND: Association of the HLA-DRB1*1501 allele with multiple sclerosis is well established, but its association with neuromyelitis optica has only been evaluated in small populations. METHODS: We performed a case-control genetic association study to evaluate the association of HLA-DRB1*1501 with neuromyelitis optica. The single nucleotide polymorphism rs3135388, which tags HLA-DRB1*1501, was genotyped in 164...
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