Article
The HLA DRB1*03:01 allele is associated with NMO regardless of the NMO-IgG status in Brazilian patients from Rio de Janeiro.
Journal of neuroimmunology - 15 Sept 2017
Alvarenga M P, Fernandez O, Leyva L, Campanella L, Vasconcelos C F, Alvarenga M, Papais Alvarenga R M
Abstract excerpt
The aim of this study was to analyze the HLA class II alleles in neuromyelitis optica (NMO) and MS patients from Rio de Janeiro to clarify whether the pattern of genetic predisposition in NMO is different from the one seen in MS or whether it is possible to determine specific alleles of susceptibility or resistance. The DR3 haplotype was over represented in NMO while the DR15 was over represented in MS. The...
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