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Article

The functional analysis of nonsense suppressors derived from in vitro engineered Saccharomyces cerevisiae tRNA(Trp) genes.

Gene - 30 Nov 1993

Atkin A L, Riazi M A, Greer C L, Roy K L, Bell J B

Abstract excerpt

Nonsense suppressors derived from Saccharomyces cerevisiae tRNA(Trp) genes have not been identified by classical genetic screens, although one can construct efficient amber (am) suppressors from them by making the appropriate anticodon mutation in vitro. Herein, a series of in vitro constructed putative suppressor genes was produced to test if pre-tRNA(Trp) processing difficulties could help to explain the lack...

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PMID: 8244031
DOI: 10.1016/0378-1119(93)90174-2

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