Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and molecular analysis of eight tRNA(Trp) amber suppressors in Caenorhabditis elegans.

Journal of molecular biology - 5 Sept 1990

Kondo K, Makovec B, Waterston R H, Hodgkin J

Abstract excerpt

Over 100 revertants of five different amber mutants were analyzed by Southern blot hybridization using synthetic oligomers as probes to detect a single base change at the anticodon, CCA to CTA (amber), of tRNA(Trp) genes of Caenohrabditis elegans. Of the 12 members of the tRNA(Trp) gene family, a total of eight were converted to amber suppressor alleles. All eight encode identical tRNAs; three of these are new...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Chromosome Mapping
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Molecular Sequence Data

Share to Mutation

Share to Oligonucleotide Probes

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 2398498
DOI: 10.1016/S0022-2836(05)80090-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and molecular analysis of eight tRNA(Trp) amber suppressors in Caenorhabditis elegans.PMID 2398498Read ↗

Differential expression of individual suppressor tRNA(Trp) gene gene family members in vitro and in vivo in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

The functional analysis of nonsense suppressors derived from in vitro engineered Saccharomyces cerevisiae tRNA(Trp) genes.Semantic proximity Read ↗

Construction of an opal suppressor by oligonucleotide-directed mutagenesis of a Saccharomyces cerevisiae tRNA(Trp) gene.Semantic proximity Read ↗

Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster.Semantic proximity Read ↗

Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33.Semantic proximity Read ↗

Isolation and characterization of new sus (amber) mutants of bacteriophage lambda.Semantic proximity Read ↗

Transfer RNA-mediated suppression of stop codons in protoplasts and transgenic plants.Semantic proximity Read ↗

In vivo function of mutated spliced leader RNAs in Caenorhabditis elegans.Semantic proximity Read ↗

Suppressors of the organ-specific differentiation gene pha-1 of Caenorhabditis elegans.Semantic proximity Read ↗

Functional differences among the six Saccharomyces cerevisiae tRNATrp genes.Semantic proximity Read ↗

Translational nonsense codon suppression as indicator for functional pre-tRNA splicing in transformed Arabidopsis hypocotyl-derived calli.Semantic proximity Read ↗

Plant nonsense suppressor tRNA(Tyr) genes are expressed at very low levels in vitro due to inefficient splicing of the intron-containing pre-tRNAs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.