Article
Systemic lupus erythematosus-related autoantibody production in mice is determined by bone marrow-derived cells.
Bone marrow transplantation - 1 Sept 1993
Levite M, Zinger H, Mozes E, Reisner Y
Abstract excerpt
Experimental systemic lupus erythematosus (SLE) can be induced in mice by immunization with either a human monoclonal anti-DNA antibody bearing the 16/6 idiotype (16/6 Id) or with a mouse monoclonal anti-idiotypic antibody specific for the 16/6 Id. Susceptibility to the induction of experimental...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Anti-Idiotypic
- Antibodies, Antinuclear
- Antibodies, Monoclonal
- Autoantibodies
- Autoimmune Diseases
- B-Lymphocytes
- Bone Marrow Cells
- Bone Marrow Transplantation
- Genetic Predisposition to Disease
- Immunization
- Immunoglobulin Idiotypes
- Lupus Erythematosus, Systemic
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Molecular Sequence Data