Article
Pituitary corticotroph function during the stress hyporesponsive period in neonatal rats.
Neuroendocrinology - 1 Jun 1993
Walker S J, Vrana K E
Abstract excerpt
Rats undergo a period in early postnatal development during which they exhibit a reduced response to stress (stress-hyporesponsive period, SHRP). SHRP is marked by a reduced capacity to secrete adrenocorticotropin (ACTH) and corticosterone in response to stressful stimuli. To characterize pituitary responsiveness during this period, we examined the release of ACTH from cultured pituitary cells derived from rats...
Topics
- Adrenocorticotropic Hormone
- Aging
- Animals
- Animals, Newborn
- Cells, Cultured
- Corticotropin-Releasing Hormone
- Female
- Phenotype
- Pituitary Gland
- Pregnancy
- Rats
- Rats, Sprague-Dawley