Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term, Dynamic Remodelling of the Corticotroph Transcriptome and Excitability After a Period of Chronic Stress

18 Oct 2024

Abstract excerpt

Chronic stress results in long-term dynamic changes at multiple levels of the hypothalamic-pituitary-adrenal (HPA) axis resulting in stress axis dysregulation with long-term impacts on human and animal health. However, the underlying mechanisms and dynamics of altered of HPA axis function, in particular at the level of pituitary corticotrophs, during a period of chronic stress and in the weeks after its cessation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Hormones and Disorders
Share to Hormonal Regulation and Hypertension
Share to Stress Responses and Cortisol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39423299
DOI: 10.1210/endocr/bqae139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term, Dynamic Remodelling of the Corticotroph Transcriptome and Excitability After a Period of Chronic StressPMID 39423299Read ↗

Dissection of the corticotroph transcriptome in a mouse model of glucocorticoid-induced suppression of the HPA axisSemantic proximity Read ↗

The Molecular Mechanisms Underlying the Regulation of the Biological Activity of Corticotropin-Releasing Hormone Receptors: Implications for Physiology and PathophysiologySemantic proximity Read ↗

Hormones and the Stressed BrainSemantic proximity Read ↗

Differential regulation of gene expression pathways with dexamethasone and ACTH after early life seizuresSemantic proximity Read ↗

The Corticotropin-Releasing Factor Family: Physiology of the Stress ResponseSemantic proximity Read ↗

Epigenetic Control of Adaptive or Homeostatic Splicing of Alternative Exons and <i>Prolactin</i> Gene Expression During Interval-Training Activities of Pituitary CellsSemantic proximity Read ↗

Chronic variable mild stress alters the transcriptome and signaling properties of the anterodorsal bed nuceleus of the stria terminalis in a sex-dependent mannerSemantic proximity Read ↗

Have you tried switching it off and on again? Mechanisms and therapeutic prospects of resetting homeostatic set points in medicine and neuropsychiatrySemantic proximity Read ↗

Have you tried switching it off and on again? Mechanisms and therapeutic prospects of resetting homeostatic set points in medicine and neuropsychiatrySemantic proximity Read ↗

Have you tried switching it off and on again? Mechanisms and therapeutic prospects of resetting homeostatic set points in medicine and neuropsychiatrySemantic proximity Read ↗

Energy Allocation Resilience and Endocrine IntegrationSemantic proximity Read ↗

Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.